Corrigendum: Epigenetic silencing of the XAF1 gene is mediated by the loss of CTCF binding

نویسندگان

  • Georgina Victoria-Acosta
  • Karla Vazquez-Santillan
  • Luis Jimenez-Hernandez
  • Laura Muñoz-Galindo
  • Vilma Maldonado
  • Gustavo Ulises Martinez-Ruiz
  • Jorge Melendez-Zajgla
چکیده

In the Supplementary Information file originally published with this Article, Supplementary Figures 1c and 1d were incorrectly labelled as Figure 1a and 1b. In addition, Supplementary Figures 2b, 2c and 2d were incorrectly labelled as Figure 1c, 1d and 1e. Lastly, Supplementary Figures 1a, 1b and 2a were omitted. These errors have been corrected in the Supplementary Information that now accompanies the Article.

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Epigenetic silencing of the XAF1 gene is mediated by the loss of CTCF binding

XAF1 is a tumour suppressor gene that compromises cell viability by modulating different cellular events such as mitosis, cell cycle progression and apoptosis. In cancer, the XAF1 gene is commonly silenced by CpG-dinucleotide hypermethylation of its promoter. DNA demethylating agents induce transcriptional reactivation of XAF1, sensitizing cancer cells to therapy. The molecular mechanisms that ...

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2016